Welcome!

Bronchopulmonary dysplasia (BPD), a debilitating lung disease with long-term consequences, is the most common morbidity in extremely premature neonates. Male babies have a higher incidence of BPD compared to females. In this proposal, we will study how small RNAs lead to sex-specific differences in lung injury in repair. This will lead to the development of novel approaches and individualized therapeutic options for BPD.

Bronchopulmonary dysplasia (BPD), a debilitating lung disease with long-term consequences, is the most common morbidity in extremely premature neonates. Male babies have a higher incidence of BPD compared to females. In this proposal, we will study how lung injury and repair is different between male and female neonates and elucidate the molecular mechanisms modulating these sex-specific differences.

Bronchopulmonary dysplasia (BPD), a debilitating lung disease with long-term consequences, is the most common morbidity in extremely premature neonates. Male babies have a higher incidence of BPD compared to females. In this proposal, we will study how the Notch pathway could lead to sex-specific differences in lung repair after exposure to hyperoxia. This will lead to the development of novel approaches and individualized therapeutic options for BPD.